传记
教育
Postdoctoral Fellow, University of Michigan – Ann Arbor, 2014年10月 – June 2017
Postdoctoral Fellow, Medical College of Wisconsin - Milwaukee, June 2012 – 2014年10月
Ph.D., Biochemistry, University of Nebraska Lincoln, 2012
B.S., Biochemistry, University of Nebraska Lincoln, 2006
教师 Appointments
2017年至今, Assistant Professor of Biochemistry, Department of 化学, University of Nebraska Kearney
Research Interests
My research interests are focused on interfacing enzymology and systems biology in the area of fat and glucose metabolism. 整体, I am interested in combining knowledge of enzyme kinetics and mechanism with knowledge of metabolic pathways to better understand metabolic regulation and control in normal and disease states.
出版物
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莫克斯利,M.A., Vinnakota, KC, Beard DA. Systems-level computational modeling explains fuel selection switching in high capacity and low capacity running rats. (Submitted to PLOS Computational Biology, June 2017).
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莫克斯利,M.A.张，L., Christgen, S, Tanner, JJ贝克尔，DF. Identification of a Conserved Histidine As Being Critical for the Catalytic Mechanism and Functional Switching of the Multifunctional Proline Utilization A Protein. Biochemistry 56: 3078-3088 (2017).
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莫克斯利,M.A., Beard DA, Bazil JN. Global Kinetic Analysis of Mammalian E3 Reveals pH dependent NAD+ /NADH Regulation, Physiological Kinetic Reversibility, and Catalytic Optimum. Journal of biological chemistry. 291: 2712-30 (2016).
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莫克斯利,M.A., Beard DA, Bazil JN. A pH-dependent Kinetic Mechanism of Dihydrolipoamide Dehydrogenase from Multiple Organisms. Biophysical journal 107: 2993-3007 (2014).
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莫克斯利,M.A., Sanyal, N, Krishnan, N, Tanner, JJ贝克尔·DF. Evidence for hysteretic substrate channeling in the proline dehydrogenase and Δ1 -pyrroline-5-carboxylate dehydrogenase coupled reaction of proline utilization A (PutA). Journal of biological chemistry. 289: 3639-51 (2014).
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斯利瓦斯塔瓦维.兰詹·S.K., 莫克斯利米.A.亨泽尔·M.T.贝克尔·D.F.坦纳·J.J. The three dimensional structural basis of type II hyperprolinemia. J摩尔生物学. 420:176-89. (2012).
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莫克斯利,M.A.贝克尔，DF. Rapid Reaction Kinetics of Proline Dehydrogenase in the Multifunctional Proline Utilization A Protein. Biochemistry 51: 511-520 (2012).
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莫克斯利,M.A., Tanner, JJ贝克尔，DF. Steady-state kinetic Mechanism of the proline:ubiquinone oxidoreductase activity of proline utilization A (PutA) from Escherichia coli. Arch Biochem Biophys 516: 113-20 (2011).
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贝克尔,DF.朱伟. 莫克斯利米.A. Flavin Redox Switching of Protein Functions. Antioxid. Redox Signal 14(6) 1079-91 (2011) (Review).
New breakthroughs
New breakthroughs
